Etiology dengue fever, cause for dengue fever
Dengue infection is because of dengue virus (DENV), which is a unmarried-stranded RNA virus (about eleven kilobases long) with an icosahedral nucleocapsid and covered with the aid of a lipid envelope. The virus is inside the family Flaviviridae, genus Flavivirus, and the kind-specific virus is yellow fever.
The dengue virus has 4 related however antigenically wonderful serotypes: DENV-1, DENV-2, DENV-3, and DENV-four. Genetic research of sylvatic traces suggest that the four serotypes developed from a not unusual ancestor in primate populations approximately a thousand years in the past and that all four one after the other emerged right into a human urban transmission cycle 500 years in the past in both Asia or Africa. Albert Sabin speciated these viruses in 1944. Each serotype is thought to have numerous extraordinary genotypes. Viral genotype and serotype, and the collection of contamination with exceptional serotypes, seem to affect disorder severity.
Living in endemic regions of the tropics (or heat, moist climates which include the southern United States) wherein the vector mosquito thrives is an crucial chance element for infection.
Poorly deliberate urbanization combined with explosive global populace increase brings the mosquito and the human host into close proximity. Increased air journey effortlessly transports infectious sicknesses between populations.
The dengue virus has 4 related however antigenically wonderful serotypes: DENV-1, DENV-2, DENV-3, and DENV-four. Genetic research of sylvatic traces suggest that the four serotypes developed from a not unusual ancestor in primate populations approximately a thousand years in the past and that all four one after the other emerged right into a human urban transmission cycle 500 years in the past in both Asia or Africa. Albert Sabin speciated these viruses in 1944. Each serotype is thought to have numerous extraordinary genotypes. Viral genotype and serotype, and the collection of contamination with exceptional serotypes, seem to affect disorder severity.
Living in endemic regions of the tropics (or heat, moist climates which include the southern United States) wherein the vector mosquito thrives is an crucial chance element for infection.
Poorly deliberate urbanization combined with explosive global populace increase brings the mosquito and the human host into close proximity. Increased air journey effortlessly transports infectious sicknesses between populations.
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